Posted by: alisalliance | March 9, 2015

10 new antibodies to battle against cancer found: Research

10 new antibodies to battle against cancer found: ResearchLondon, Jan 22:
Researchers from Aarhus University in Denmark are reported to have developed 10 new antibodies that can be used in the battle against cancer.

These antibodies work by inhibiting the body’s blood vessel formation close to the tumor, which is, thereby, cut off from oxygen and nutrient supply.

In lab tests over mice, the team has succeeded in using these antibodies to stop the development of malignant tumors.

‘The antibodies we have found prevent a cancer tumor from growing. They appear to work perfectly in the laboratory,’ said associate professor Peter Kristensen.

The new antibodies are easier to extract and they also appear to be more effective because they hit other – and possibly stronger – signal molecules from the cancer cells.

‘We have got a large library of antibodies that can supplement the body’s own fight against disease. The major engineering challenge is identifying the ones that are relevant regarding the specific purpose,’ Kristensen explained.

The antibodies neutralize the effects of signal substances released by carcinoma cells to get blood vessels to replicate, thus cutting off the blood supply to the tumor.

A cancer tumor deprived of oxygen and nutrients becomes dormant and is, thereby, made harmless.

The researchers will now work on gaining a more in-depth understanding of the 10 antibodies.

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